- Safety & Security Systems & Consultants, Portola Valley
- Seafood Restaurants, Portola Valley
- Secondary Schools, Portola Valley
- Security Alarm Systems - Home & Business, Portola Valley
- Security Guard & Patrol Service, Portola Valley - Bodyguard, Guard Dogs, Etc
- Security Services, Portola Valley
- Shoe Stores, Portola Valley - Mens, Womens & Kids Shoes
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- Shopping & Shopping Services, Portola Valley
- Social Services & Welfare, Portola Valley
- Social Workers & Services, Portola Valley
- Specialty Animal Services, Portola Valley
- Specialty Stores, Portola Valley
- Sports & Recreational Services, Portola Valley
- Stone & Rock Quarry, Portola Valley - Gravel Pit, Shale, Granite, Limestone, Crushed Rock, etc
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