- Labor Organizations, San Bruno
- Laboratories Biological, San Bruno
- Laboratories Medical, San Bruno
- Ladies Ready To Wear, San Bruno
- Lamp Shades, San Bruno
- Lamps & Lamp Shades Retail, San Bruno - Desk, Table & Floor Lamps
- Land Surveyor, San Bruno - Land Surveying Services
- Landscape Garden Services, San Bruno
- Landscaping, San Bruno
- Late Night Restaurants, San Bruno
- Laundromats & Dry-Cleaning, Coin-Operated, San Bruno
- Lawn & Garden Services, San Bruno
- Lawn Maintenance Services, San Bruno
- Lawyers & Attorneys, San Bruno
- Leather Goods, San Bruno
- Leather Tanning & Finishing Manufacturers, San Bruno
- Legal & Tax Services, San Bruno
- Legal Professionals, San Bruno
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- Libraries, San Bruno
- Life Insurance, San Bruno
- Lighting Fixtures & Equipment, San Bruno
- Lighting Fixtures Repair, Maintenance & Installation, San Bruno
- Limousine Service, San Bruno
- Lingerie & Underwear for Women, San Bruno - Bras, Panties, Bustiers, Corsets & More
- Liquor Stores, San Bruno
- Loans Personal, San Bruno
- Locks, San Bruno
- Locksmiths, San Bruno - Residence, Commercial, Safe & Auto Car Locksmith
- Locksmiths Equipment & Supplies, San Bruno
- Lodging, San Bruno
- Lodging Hostels, San Bruno
- Lodging Services, San Bruno
- Logistics Freight, San Bruno
- Long Haul Trucking Companies, San Bruno
- Lubricating Oils , San Bruno - Motor Oil
- Lutheran Church, San Bruno
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