- U-Haul Truck Rental, San Francisco - U-Haul Moving
- U-Haul Trucks, San Francisco - Uhaul Truck Rental
- U.S. Postal Service, San Francisco
- Ultrasound Services, San Francisco
- Umbrellas Retail, San Francisco
- Undergarments & Nightwear Manufacturers, San Francisco
- Underground Utility Locating Service, San Francisco
- Unfinished Furniture, San Francisco
- Unfurnished Apartments, San Francisco
- Uniforms, Work Clothes & Safety Clothing, San Francisco
- Unitarian Universalist Churches, San Francisco
- Unity Church, San Francisco
- Universal Church, San Francisco
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- Upholsterers Supplies & Equipment, San Francisco
- Upholstery Fabric Stores , San Francisco
- Upholstery Fabrics Manufacturers, San Francisco
- Urologists, San Francisco - Urology Doctors, Physicians & Surgeons
- Used Appliances, San Francisco
- Used Book Stores, San Francisco - New & Rare Books
- Used Cars, Truck, Van & SUV Car Dealerships, San Francisco
- Used Furniture Stores, San Francisco - Used Office, Patio, Hotel, Baby & Bedroom Furniture Dealers
- Used Merchandise, Resale Shops & Thrift Stores, San Francisco
- Utilities, San Francisco
- Utility & Waste Management Services, San Francisco
- Utility Trailer Rental, San Francisco
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