- Obstetricians & Gynecologists, Downey - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Occupational Health Care Professionals, Downey
- Occupational Therapy, Downey - Occupational Health Specialists
- Office & Meeting Equipment & Supplies Rental, Downey
- Office Buildings & Parks, Downey
- Office Supplies, Equipment & Office Furniture Stores, Downey
- Oil & Petroleum Products, Downey - Merchant, Wholesalers, etc
- Oil Change & Lubrication, Downey - Auto Oil & Quick Lube
- Oil Industry & Oil Field Equipment & Services, Downey - Oil Companies
- Oil Refinery, Downey
- Ophthalmologists, Downey - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Goods Repair & Service, Downey - Camera Repair
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Downey
- Opticians, Downey
- Optometrists, Downey - Eye Doctors, Physicians & Surgeons (Optometry)
- Oral Surgeon, Downey - Dentists - Oral & Maxillofacial Surgeons
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- Ornamental Metal Work, Downey - Steel, Iron, Bronze, etc
- Ornamental Nursery, Downey
- Ornamental Nursery Services, Downey
- Orthodontist, Downey - Teeth Straightening, Invisalign & Dental Braces
- Orthodox Churches, Downey
- Orthopedic & Prosthetic Appliances & Shoes, Downey - Orthopedic Shoes
- Orthopedic Shoes, Downey
- Orthopedists, Downey - Orthopedic Surgery Doctors, Physicians & Surgeons
- Orthotics and Prosthetics, Downey
- Other Building Materials & Supplies, Downey
- Other Lodging, Downey
- Outdoor & Lawn & Garden Equipment Repair & Service, Downey
- Outdoor Equipment & Accessories, Downey
- Outerwear Stores, Downey - Jackets, Sunglasses, Hats, Caps, Coats, Gloves & More
- Outpatient Clinics, Downey - Care & Treatment Centers
- Outsourcing Services, Downey
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