- Salted & Roasted Nuts & Seeds Manufacturers, Kelseyville
- Secondary Schools, Kelseyville
- Security Investigative Services, Kelseyville
- Security Services, Kelseyville
- Senior Citizens Service & Health Organizations, Kelseyville
- Septic Tanks & Septic Systems Contractors, Kelseyville - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Service Establishment Supplies & Equipment, Kelseyville
- Sewer & Drain Cleaning & Repair, Kelseyville - Drain Cleaner & Installation Services
- Sewing & Yarn Stores & Supplies, Kelseyville
- Sheet Metal Contractors, Kelseyville - Sheet Metal Fabrication
- Sheet Metal Fabricators & Ductwork Contractors, Kelseyville
- Shopping & Shopping Services, Kelseyville
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- Small Appliances, Kelseyville
- Soaps & Cosmetics, Kelseyville
- Social Services & Welfare, Kelseyville
- Societies & Foundation Associations, Kelseyville
- Specialty Stores, Kelseyville
- Specialty Vehicle Rental & Leasing, Kelseyville
- Sporting Goods Stores, Kelseyville
- Sprinkler Alarm Systems, Kelseyville - Fire Sprinkler Systems
- State Government, Kelseyville
- Stone & Rock Quarry, Kelseyville - Gravel Pit, Shale, Granite, Limestone, Crushed Rock, etc
- Surveyor Services, Kelseyville - Surveying Service
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