- Safe & Vault, Placerville
- Safe, Lock & Key Repair Services, Placerville - Safes & Vaults Opening & Repair
- Safety & Security Systems & Consultants, Placerville
- Safety Training Schools, Placerville
- Sand Gravel & Aggregate, Placerville
- Sandwich Shop Restaurants, Placerville
- Sanitary Engineers, Placerville
- Satellite & Cable TV Equipment & Systems Repair & Service, Placerville
- Satellite TV Service, Placerville
- Savings & Loan Associations, Placerville
- Savings Banks, Placerville
- Scales Public, Placerville
- Scales Retail, Placerville
- Scanning Service, Placerville
- Schools Montessori Instruction, Placerville
- Scientific & Laboratory Equipment & Instruments, Placerville
- Scrap & Waste Materials, Placerville
- Screen Printing, Placerville
- Seafood Restaurants, Placerville
- Seals, Placerville - Hermetic, Hydraulic, Mechanical, Metal, Oil, Grease, etc
- Secondary Schools, Placerville
- Secretarial & Court Reporting Services, Placerville
- Security & Surveillance System & Equipment, Placerville
- Security Alarm Systems - Home & Business, Placerville
- Security Brokers & Dealers, Placerville
- Security Consultants, Placerville
- Security Services, Placerville
- Senior Citizens Service & Health Organizations, Placerville
- Septic Tank Pumping & Cleaning, Placerville - Septic Systems
- Septic Tanks & Septic Systems Contractors, Placerville - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Septic Tanks & Systems Inspection, Placerville
- Service Establishment Supplies & Equipment, Placerville
- Sewer & Drain Cleaning & Repair, Placerville - Drain Cleaner & Installation Services
- Sewing & Yarn Stores & Supplies, Placerville
- Sharpening Service, Placerville
- Sheet Metal, Placerville
- Sheet Metal Contractors, Placerville - Sheet Metal Fabrication
- Sheet Metal Fabricators & Ductwork Contractors, Placerville
- Shirts & T-Shirts, Placerville
- Shoe Repair Shops, Placerville
- Shoe Store - More, Placerville
- Shoe Stores, Placerville - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Placerville
- Shutters - Interior & Exterior, Placerville - Wood, Vinyl, Window, Plantation Shutters, etc
- Sign Equipment & Supplies, Placerville
- Signs, Placerville
- Silversmiths & Goldsmiths, Placerville
- Silverware & Plated Ware, Placerville
- Skateboards & Equipment Shops, Placerville - Skateboarding Supplies
- Skating Supplies, Placerville - Ice, Inline, Speed, Figure & Roller Skates
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- Skin Care & Cosmetology Salons, Placerville
- Skin Care Products & Treatments, Placerville
- Skylights, Placerville - Skylight Shades, Blinds, Covers & More
- Small Appliances, Placerville
- Small Business & Office Equipment Repair Services, Placerville
- Smog Check, Brake & Lamp Inspection & Repair, Placerville
- Snack Foods, Placerville
- Snacks & Desserts, Placerville
- Social Security And Disability Attorneys & Lawyers, Placerville
- Social Security And Disability Lawyers & Attorneys, Placerville
- Social Services & Welfare, Placerville
- Social Workers & Services, Placerville
- Societies & Foundation Associations, Placerville
- Solar Energy Companies - Contractors, Placerville - Solar Panel Installation - Solar Power Systems
- Solariums & Garden Rooms, Placerville
- Sound Systems, Microphones & Equipment, Placerville
- Soup & Salad Restaurants, Placerville
- Space Heaters, Placerville
- Special Education & Care, Placerville
- Special Events & Party Supply Rental, Placerville
- Special Events Photographers, Placerville
- Special Interest Schools Or Instruction, Placerville
- Speciality Food Stores, Placerville
- Specialty Animal Services, Placerville
- Specialty Stores, Placerville
- Speech & Hearing Specialists, Placerville
- Speech & Language Therapy, Placerville
- Sporting Goods Equipment Rental, Placerville
- Sporting Goods Stores, Placerville
- Sports Medicine, Placerville - Doctors, Physicians & Surgeons
- Sprinkler Alarm Systems, Placerville - Fire Sprinkler Systems
- Sprinkler System Contractors, Placerville - Garden & Lawn Sprinkler System Installation & Repair
- Staffing & Support Services, Placerville
- Stamp Collecting & Coin Dealers , Placerville
- State Government, Placerville
- Steel & Metal Goods, Placerville - Steel Distributors
- Steel Detailers, Placerville
- Steel Manufacturers, Placerville
- Steel Work Contractors, Placerville
- Stocks & Bond Brokers, Placerville
- Store Fixtures & Display Equipment, Placerville
- Stoves & Furnace Equipment, Placerville - Fittings & Repair Parts
- Substance Abuse Clinics, Placerville - Alcoholism, Addiction & Drug Abuse Treatment Centers
- Surveyor Services, Placerville - Surveying Service
- Sushi Restaurants, Placerville
- Sweepers & Scrubbers Industrial, Placerville - Sweeping Service
- Swimming Pool, Sauna & Spa Contractors, Placerville
- Swimming Pools Contractors, Placerville - Install Inground - Above Ground Pools
- Swimming Pools Repair, Service, Supplies, Sale & Installation, Placerville
- Swimming Pools Supplies, Equipment & Accessories, Placerville
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